Assessing musculoskeletal symptoms throughout the menopause transition

Menopause, typically experienced by women and female-presenting individuals around ages 45–55, involves a significant drop in estrogen, causing symptoms beyond hot flashes. One critical but under-recognized set of symptoms affects muscles, joints, and bones, resulting in pain, weakness, and reduced bone density. These are known as musculoskeletal (MSK) symptoms. Approximately 70% of women experience MSK symptoms during menopause, with about 25% severely impacted. These symptoms significantly raise the risk of falls, fractures, and loss of independence. Despite the significant impact these symptoms have on daily life, very little is known about how Canadian women experience and manage these problems daily. Our research addresses this gap by analyzing real-world data collected from women visiting St. Joseph’s Menopause Clinic in Hamilton, Ontario. We will examine how these MSK symptoms vary across different menopause stages, and evaluate how effective common treatments like hormone therapy, antidepressants, and pain medications truly are in relieving these problems. By taking this approach, our project is uniquely positioned to uncover insights that matter to women and healthcare providers alike. This involves helping older women stay active, independent, and healthier longer.