Michael Surette is a professor of medicine and Canada Research Chair in interdisciplinary microbiome research. He leads the laboratory for microbiome and polymicrobial research at McMaster University. Michael’s research investigates the role of normal flora-pathogen interactions in health and disease in the area of respiratory infections with a focus in cystic fibrosis. A polymicrobial perspective on these infections has led to identification of overlooked pathogens in airway disease as well as synergistic interactions between avirulent organisms and pathogens. This is a fundamentally different view of airway infections and has led to direct benefits to patients through altered treatment strategies. Michael’s latest academic article focuses on age-related systemic inflammation and macrophage dysfunction.