Secondary analysis of shared risk factors affecting osteoarthritis, cardiovascular disease, aging and mobility

Osteoarthritis, a progressive joint disease involving breakdown of cartilage and bone, has become the most prevalent cause of physical disability in older adults. There is a greater risk of cardiovascular disease (e.g., ischemic heart disease, heart failure), stroke, and dementia with osteoarthritis. This research explores overlapping shared risk factors for the onset and/or progression of cardiovascular disease and osteoarthritis. Through machine learning approaches, Mei aims to identify potentially overlapping mechanisms between these age-associated diseases. This information will aid in managing the onset and progression of these conditions that affect mobility, independence and, subsequently, quality of life in the Canadian aging population.