Saman Sadeghi

Overview

Saman Sadeghi’s research is focused on the discovery, preclinical validation and clinical translation of molecular imaging agents. Molecular imaging can detect early-stage age related changes in the brain associated with neurodegenerative diseases, including Alzheimer’s, Parkinson’s and Huntington’s disease. For example, in vivo imaging can detect various components of age-associated molecular processes, such changes in neurotrophic factors or bioenergetic impairments through PET imaging of mitochondrial activity. Diagnostic imaging can identify aging individuals who are at risk for progression of specific diseases so that they can benefit from precisely targeted interventions. Molecular imaging can also enable earlier and more accurate diagnosis of aging related musculoskeletal system diseases such as development of osteoarthritis.

Affiliations

• Member, McMaster Institute for Research on Aging (MIRA), McMaster University
• Associate Professor, Chemistry and Chemical Biology, Science, McMaster University
• Adjunct Professor, Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles

Education

• BASc (Engineering), University of Toronto
• PhD, University of Toronto
• Postdoctoral Scholar, University of California, Los Angeles, USA

Additional Links

• McMaster Radio Chemistry