John McDonough
Dr. John McDonough has been appointed Assistant Professor in the Department of Medicine, Division of Respirology, effective September 1, 2023.
Dr. McDonough completed his PhD in Experimental Medicine at the University of British Columbia. Following his PhD, he became a Research Associate at Imperial College, UK then obtained a research fellowship to work with the lung transplant group at KU Leuven, Belgium, where he developed novel 3D imaging techniques to study lung disease. He was then recruited as an Instructor to the Pulmonary Critical Care & Sleep Medicine section at Yale University where he developed skills in single cell transcriptomics.
Dr. McDonough’s lab will apply advanced 3-dimensional imaging technologies like microCT combined with single cell RNA-sequencing and spatial transcriptomics to better understand the fundamental structural and mechanistic changes that underlies normal aging of the lung and age-related lung diseases, including COPD and IPF. His laboratory will have two primary focus areas: (1) understanding the role of ferroptosis in development of emphysema in COPD and (2) understanding the structural changes associated with honeycomb cyst development in IPF
Affiliations
- Director of the Molecular Phenotyping and Imaging Core (MPIC), Firestone Institute of Respiratory Health, Hamilton, Canada
- Assistant Professor in the Department of Medicine, Division of Respirology, effective September 1, 2023.
- American Thoracic Society (ATS) Respiratory Structure & Function Planning Committee member (2021-present)
- American Thoracic Society (ATS) Respiratory Structure & Function Programming Committee member (2022-present)
- Scientific Symposia Organizer ATS 2023
Education
- B.Sc. Biological Sciences, Simon Fraser University, Burnaby, BC
- M.Sc. in Experimental Medicine, University of British Columbia, Vancouver, BC
- Ph.D. in Experimental Medicine, University of British Columbia, Vancouver, BC
