MIRA researchers among teams awarded over $16 million in CIHR funds

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Original story by Faculty of Health Sciences, Written by Mike Ayers

The Canadian Institutes of Health Research (CIHR) has awarded over $16 million to research teams across McMaster University’s Faculty of Health Sciences (FHS), as a result of recent funding announcements for Project Grants, as well as Planning and Dissemination Grants.

Funded projects across FHS seek to investigate a variety of important topics, from validifying how wearable technology can assess mobility in older adults, fighting diverse forms of cancer, to developing the latest food allergy clinical practice guidelines.

“Our researchers are driving the future of health science innovation,” says Jonathan Bramson, vice-dean of research for the Faculty of Health Sciences. “The depth and breadth of our expertise continues to fuel impactful discoveries, reinforcing McMaster’s global leadership in transformative research that improves lives worldwide.”

The following FHS projects were awarded funding in the recent announcements:

Advancing justice-oriented patient partnership for more equitable health systems: Knowledge dissemination strategy for the Canadian Patient Partner Study (CPPS)

Julia Abelson, Department of Health Research Methods, Evidence, and Impact

Building engagement capable environments for health system transformation: An implementation study

Julia Abelson, Department of Health Research Methods, Evidence, and Impact

SMARTMOVE: Validating real-world mobility outcomes derived from wearable technology in older Canadians

Marla BeauchampJulie Richardson, School of Rehabilitation Science

Planning a Systems Approach to Decreasing Inappropriate Psychotropic Medication Use in Long Term Care Homes

Sophiya Benjamin, Department of Psychiatry & Behavioural Neurosciences

Barriers and facilitators for developing and implementing evidence-based practice guidelines during a pandemic: An exploratory mixed-methods study

Romina Brignardello, Department of Health Research Methods, Evidence, and Impact

Facilitating antibiotic stewardship: evaluating the trustworthiness, adaptability, and extent to which antimicrobial resistance is considered in antimicrobial evidence-based practice guidelines

Romina Brignardello, Department of Health Research Methods, Evidence, and Impact; Mark Loeb, Department of Pathology & Molecular Medicine

Food allergy: A Clinical Practice Guideline

Derek Chu, Department of Medicine

Multistakeholder Knowledge Dissemination Meeting REVISE: Re-Evaluating the Inhibition of Stress Erosions in the ICU Trial

Deborah Cook, Department of Medicine

Planning the Launch of the Canadian Obstetric Survey System in Ontario for Severe Maternal Morbidity by Engaging an Interdisciplinary Group of Experts

Rohan D’Souza, Department of Obstetrics & Gynecology

The global burden and contributing factors to COPD in high-, middle- and low-income countries

Mylinh DuongSalim Yusuf, Department of Medicine; Shrikant Bangdiwala, Department of Health Research Methods, Evidence, and Impact; Guillaume Pare, Department of Pathology & Molecular Medicine

Biophysical Society of Canada 2025 Annual Meeting

Cecile Fradin, Department of Biochemistry & Biomedical Sciences

Systematic single-cell characterization of coordinated RNA regulatory mechanisms underlying glioblastoma progression

Hong Han, Department of Biochemistry & Biomedical Sciences

QT-prolonging Medications and Major Adverse Cardiac Events (QTP-MACE)

Anne Holbrook, Department of Medicine

Intravascular Ultrasound for Peripheral Artery Disease Revascularization: The CLARITY Randomized Controlled Trial

Sanjit Jolly, Department of Medicine; John Harlock, Department of Surgery

Prospective Global Platform to Evaluate and Enhance Cognitive and Functional Trajectories after Stroke (PROSPECT)

Raed JoundiMukul Sharma, Department of Medicine

Microbiome determinants of impaired wound healing

Lindsay Kalan, Department of Biochemistry & Biomedical Sciences

Liraglutide for patients receiving Endovascular Stroke Thrombectomy (LEAST)

Aristeidis KatsanosMukul SharmaAshkan Shoamanesh, Department of Medicine

Randomized trial Evaluating first time shoulder Dislocation: Surgery vs Conservative care (REDUCE)

Moin Khan, Department of Surgery

A novel strategy to reduce intestinal inflammation and fibrosis by 5-methoxytryptophan (5-MTP)

Waliul Khan, Department of Pathology and Molecular Medicine

Elucidating the role of memory B and T cells in recall allergic IgE responses

Joshua Koenig, Department of Medicine

Endothelial cell senescence drives progression of pulmonary fibrosis

Martin Kolb, Department of Medicine

Collaborative development of research reporting guidelines for health research involving incarcerated populations: The RESPECT Guidelines Project

Fiona Kouyoumdjian, Department of Family Medicine

Advanced pre-clinical development of selective IMPDH2 inhibitors for the treatment and prevention of brain metastases

Jakob Magolan, Department of Biochemistry & Biomedical Sciences

The Comprehensive Antibiotic Resistance Database: From Genes to Interpretation

Andrew McArthur, Department of Biochemistry & Biomedical Sciences

An Individual Participant Data Meta-Analysis of Two Randomized Controlled Trials Assessing Oral Anticoagulation for Device-detected Atrial Fibrillation

William McIntyre, Department of Medicine

Structural Basis of PKG-Targeting Therapies and Aberrant cGMP Signaling ($990,675)

Giuseppe Melacini, Department of Biochemistry & Biomedical Sciences

Systemic administration of oncolytic BHV-1 to target multiple cancer indications and the role of therapy-induced immunity

Karen Mossman, Department of Medicine

LEANing into SERENE: Engaging people with lived and living experience in research on severe maternal morbidity

Giulia MuracaRohan D’Souza, Department of Obstetrics & Gynecology; Benicio FreySheryl Green, Department of Psychiatry & Behavioural Neurosciences; Susan Jack, School of Nursing

Mode of operative delivery in the second stage of labour and risk of subsequent spontaneous preterm birth

Giulia Muraca, Abirami Kirubarajan, Department of Obstetrics & Gynecology

Soft-tissue Quadriceps autograft ACL-reconstruction in the Skeletally immature vs. Hamstrings (SQuASH)

Darren de SaOlufemi Ayeni, Department of Surgery

Psychometric evaluation of the McMaster Cough Severity Questionnaire: a new cough severity instrument for patients with chronic cough

Imran Satia, Department of Medicine

Targeting BACE1 for the prevention and treatment of Brain metastases ($975,375)

Sheila Singh, Department of Surgery

A Multisectoral Planning Meeting to Co-Develop Criteria for Tracking Canadian Hospital Research Landscape

Jennifer Tsang, Department of Medicine

Co-creating a national evidence base for the development, implementation, and evaluation of learning health systems in Canada

Carly Whitmore, School of Nursing

Prospective Randomized Evaluation of Emerging Novel Treatments for Infection Prophylaxis in Total Joint Replacement (PREVENT-iT)

Thomas WoodMohit BhandariSameer Parpia, Department of Surgery

Visit the CIHR grants decision notification page to learn more about these recent announcements.